Endocrine Abstracts

Section 1: Case History: A 28 year old female initially presented to Endocrinology in 2020 with hirsutism and irregular menstruation but reassuring biochemistry. In 2022, she was referred to Gastroenterology with weight loss, vomiting and dyspepsia and found to have severe hyperprolactinaemia. Past medical history included anxiety/depression. Current medication was esomeprazole 40mg OD and mebeverine 135mg TDS. Cyclizine 50mg TDS had previously been prescribed, followed by dom...

A 31 year old female patient initially presented with a two month history of unintentional weight loss. Past medical history included multiple sclerosis, for which she had last received alemtuzumab immunotherapy five months previously. Thyroid function tests (TFTs) demonstrated hyperthyroidism, with Thyroid Stimulating Immunoglobulins (TSI) 5.71 iu/l(NR: <0.56). She was diagnosed with Graves’ disease, possibly induced by alemtuzumab, and commenced on carbimazole. She ...

Background: Thioamide-resistant severe Graves’ thyrotoxicosis (SGT) is rare and often poor patient adherence to therapy is suspected. Management is truly challenging. Case report: 36-year-old female with SGT was referred for further management. The diagnosis was made 5 years ago following delivery of her first son. During her second pregnancy 2 years ago, she required emergency caesarean with the indication of foetal tac...